Preheat the oven to 400 degrees. In a small bowl, combine the garlic powder, onion powder, basil, oregano, salt, and pepper. Set aside.
Slice each chicken breast in half horizontally to create two thin chicken cutlets. Sprinkle the spice blend over both sides of the chicken. Place the chicken on a sheet pan. Bake for 15-20 minutes or until the chicken reaches an internal temperature of 165 degrees.
Top each chicken cutlet with 1 tablespoon pizza sauce, 1 slice cheese, and 3 slices of pepperoni.
Turn the oven to broil and cook the chicken for 1-2 minutes until the cheese is melted.